|
Famotidine occurs as histamine H2-receptor antagonist that inhibits stomach acid production, and is commonly used in the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).
Clinical use
Independent article: H2-receptor antagonist
Certain preparations of pepcid come available over the counter (OTC) in various countries. around the United States, preparations of Decade mg tablets, occasionally in combination by having the extra traditional antacid (brand name Pepcid Complete), are available OTC. Big drugs however demand the guide.
History and development
Famotidine was developed by Merck & Co.. A imidazole-ring of cimetidine was replaced with the Two-guanidinothiazole ring. Famotidine proved to become Thirty days additional active than cimetidine.
It wwhen 1st marketed (as Pepcidine® & Pepcid®) inside 1985. Pepcid RPD® (orally disintegrating tablets that are non swallowed) was freed within 1999. Generic forms (e.g. Fluxid®, Schwarz Pharma) became available around 2001.
|